In humans, the symptoms of monkeypox are similar to but milder than the symptoms of monkeypox. Monkeypox begins with fever, headache, muscle aches. Monkeypox begins with fever, headache, muscle aches and exhaustion. The main difference between the symptoms of smallpox and monkeypox is that monkeypox causes lymph nodes to swell (lymphadenopathy), while smallpox does not.
The incubation period (time from infection to symptoms) for monkeypox is usually 7 to 14 days, but can range from 5 to 21 days. Symptoms usually start with fever, headache, back pain and lethargy, which lasts one to two days, Lewis said. Next, a rash will appear, which starts as a red discoloration on the skin. It usually starts in the face and then progresses to the arms and legs, then to the hands and feet, and finally to the rest of the body.
This phase also lasts one to two days. Then comes what is known as papules, when the rash rises on the skin, rather than flat. This also lasts one to two days. Most patients experience only fever, body aches, chills, and fatigue.
People with a more serious illness may develop a rash and lesions on the face and hands that may spread to other parts of the body. The illness usually starts with flu-like symptoms, such as fever, headache, muscle aches, and exhaustion, which may last a day or two. A rash often appears one to three days after the fever, which progresses from red areas to small bumps on the skin. These can become blisters that can be filled with whitish liquid.
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